Foundational reagents for high-throughput biology.
High-performance, radically transparent cell-free reagents—engineered for throughput from screening to scale.
What We Do
We produce foundational reagents for biological R&D.
Our first focus: cell-free protein reagents that work in two modes—screening (many variants, fast turnaround) and scale-up (mg quantities)—with industry-leading economics designed to stay competitive with traditional cellular expression.
Why Sepia
Transparent by design. Built to scale.
High yield
~2 mg/mL for well-expressing proteins
Low cost
pricing as low as $25/mL (vs. ~$1,330/mL typical kit pricing)
Built to scale
optimized for both screening and mg-scale production
Radical transparency
formulations documented so you know what you’re running
Flexible by design
compatible with linear DNA, plasmid DNA, and low DNA working concentrations
Reliable QC
extensive lot-level QC data to support standardization
Biology, Unlocked
Commoditizing biological R&D.
We’re enabling any scientist to run modern high-throughput biology—reliable, affordable, transparent tools that scale with your ambition.
For teams that…
- Need to screen dozens to thousands of protein variants quickly
- Want milligram-scale protein on demand for assays, characterization, and downstream work
- Are working on challenging proteins (toxic, unstable, insoluble, multi-domain, or otherwise difficult in cells)
- Prefer transparent systems they can understand, troubleshoot, and standardize
- Want CFPS that fits into existing workflows (plates, automation, common incubators)
OpenCFPS™ Cell-free Protein Synthesis